

High-throughput discovery of inhibitory protein fragments with AlphaFold
A. Savinov, S. Swanson, A.E. Keating, & G. Li, Natl. Acad. Sci. U.S.A. 122 (6) e2322412122, https://doi.org/10.1073/pnas.2322412122 ...
차혜욱
4월 9일1분 분량


GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke
Zhang Y, Wu Z, Huang Z, Liu Y, Chen X, Zhao X, He H, Deng Y. Brain Res. 2022 Mar 1;1778:147768. doi: 10.1016/j.brainres.2021.147768....
임지현
4월 9일6분 분량


Novel drug targets in 2024
By Sorin Avram , Liliana Halip , Ramona Curpan & Tudor I. Oprea BIOBUSINESS BRIEFS 04 April 2025 Nature reviews drug discovery In 2024,...
한울 전
4월 9일5분 분량


Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma
Mary Jane Lim-Fat # 1 , J Bryan Iorgulescu # 2 , Rifaquat Rahman 3 , Varun Bhave 4 , Alona Muzikansky 5 , Eleanor...
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4월 5일3분 분량


A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma
Veronica Rendo1,2,3,4,5*†, Eudocia Q. Lee1,3,6*†, Connor Bossi7, Nicholas Khuu1,2,4, Michelle A. Rudek8‡, Sangita Pal1,2,3,4, Narmen...
한울 전
4월 5일3분 분량


Contemporary prognostic signatures and refined risk stratification of gliomas: An analysis of 4400 tumors
Hia S. Ghosh‡, Ruchit V. Patel‡, , Eleanor Woodward, Noah F. Greenwald, Varun M. Bhave, Eduardo A. Maury, Gregory Cello, Samantha E....
한울 전
4월 5일3분 분량


Disproportionately Enlarged Subarachnoid-Space Hydrocephalus on MRI in Pathologically Confirmed Progressive Supranuclear Palsy
Miki Kawazoe, 1,2 Shunsuke Koga, 1 Hiroaki Sekiya, 1 Keith Anthony Josephs, 3 Neill R. Graff-Radford,4 and Dennis W. Dickson 5 Neurology:...
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4월 4일3분 분량


Unbiased CSF Proteomics in Patients With Idiopathic Normal Pressure Hydrocephalus to Identify Molecular Signatures and Candidate Biomarkers
de Geus MB, Wu CY, Dodge H, Leslie SN, Wang W, Lam TT, Kahle KT, Chan D, Kivisäkk P, Nairn AC, Arnold SE, Carlyle BC. Neurology. 2025 Mar...
한울 전
4월 4일4분 분량


Efficacy of Adding Veliparib to Temozolomide for Patients With MGMT-Methylated Glioblastoma: A Randomized Clinical Trial
Shu-Ling Chong, M.D. Yanan Zhu, PhD. et al. 2025년 3월 11일 JAMA Netw Open 2025; 8(3):e250438 DOI: 10.1001/jamanetworkopen.2025.0438...
정소영
4월 4일3분 분량


Direct oral anticoagulants versus no anticoagulation for the prevention of stroke in survivors of intracerebral haemorrhage with atrial fibrillation (PRESTIGE-AF)
Veltkamp, RolandNaegel, Steffen et al. The Lancet, Volume 405, Issue 10482, 927 - 936 https://www.thelancet.com/journals/lancet/article/P...
한울 전
4월 2일3분 분량


Safety and efficacy of atorvastatin for rebleeding in cerebral cavernous malformations (AT CASH EPOC): a phase 1/2a, randomised placebo-controlled trial
Awad, Issam A et al. The Lancet Neurology, Volume 24, Issue 4, 295 - 304 https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(...
한울 전
4월 2일3분 분량


Association Between Changes in White Matter Volume Detected With Diffusion Tensor–Based Morphometry and Motor Recovery After Stroke
Matthew A. Edwardson, 1,2 Amritha Nayak,3,4,5 M. Okan Irfanoglu, 3 Marie L. Luby, 6 Lawrence L. Latour, 6 and Carlo Pierpaoli 3 Neurology...
한울 전
4월 2일3분 분량


Brain Death/Death by Neurologic Criteria Determination
Ariane Lewis, M.D; Matthew P. Kirschen, M.D, PhD 2021년 10월 1일 Continuum (Minneap Minn). 2021Oct 1;27(5):1444-1464. DOI:...
이정희
4월 2일2분 분량


General Anesthesia Versus Conscious Sedation in Thrombectomy Patients With Low NIHSS Anterior Circulation Stroke
Christian Heitkamp, Fabian Flottmann, Tobias D. Faizy, Alexander Heitkamp, Christian Thaler, Vincent Geest, Maximilian Schell, Helge C....
한울 전
4월 1일3분 분량


Ventilation practices in acute brain injured patients and association with outcomes: the VENTIBRAIN multicenter observational study
Robba C, Giardiello D, Almondo C, Asehnoune K, Badenes R, Cinotti R, Elhadi M, Graziano F, Helbok R, Jiang L, Chen W, Laffey JG, Messina...
한울 전
4월 1일3분 분량


Clinical Outcomes of Hypertonic Saline vs Mannitol Treatment Among Children with Traumatic Brain Injury
Shu-Ling Chong, M.D. Yanan Zhu, PhD. et al. 2025년 3월 11일 JAMA Netw Open 2025; 8(3):e250438 DOI: 10.1001/jamanetworkopen.2025.0438...
이정희
4월 1일3분 분량


Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury
Lan Y, Zhang X, Liu S, Guo C, Jin Y, Li H, Wang L, Zhao J, Hao Y, Li Z, Liu Z, Ginhoux F, Xie Q, Xu H, Jia JM, He D. Immunity. 2024 Feb...

이은엽
3월 31일2분 분량


Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury
Jan Claassen. M.D. et al. 2019년 6월 26일 N Engl J Med 2019;380:2497-2505. DOI: 10.1056/NEJMoa1812757 Background Brain activation in...
이정희
3월 31일3분 분량


Computational drug repurposing:approaches, evaluation of in silicoresources and case studies
Nat Rev Drug Discovery. 2025 Mar 18. doi: 10.1038/s41573-025-01164-x. [작성자: 전한울] Abstract Repurposing of existing drugs for new...
한울 전
3월 30일4분 분량


Targeted protein degradation: from mechanisms to clinic
Nat Rev Mol Cell Biol 25 , 740–757 (2024) https://doi.org/10.1038/s41580-024-00729-9 Targeted protein degradation refers to the use of...
한울 전
3월 30일3분 분량